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Article

Genetic convergence of Parkinson's disease and lysosomal storage disorders.

Molecular neurobiology - 1 Jan 2015

Deng Hao, Xiu Xiaofei, Jankovic Joseph

Abstract excerpt

Parkinson's disease is a common progressive neurodegenerative disorder characterized by predominant degeneration of the dopaminergic neurons in the substantia nigra pars compacta and the presence of intracellular inclusions enriched in α-synuclein, resulting in a variety motor and nonmotor symptoms. Lysosomal storage disorders are a group of disorders including Gaucher disease, Niemann-Pick disease, and neuronal...

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Source

Identifiers

PMID: 25099932
DOI: 10.1007/s12035-014-8832-4

Genes

NPC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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