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Article

Guanine nucleotide‐binding protein 1 is one of the key molecules contributing to cancer cell radioresistance

5 Aug 2014

Abstract excerpt

Standard fractionated radiotherapy for the treatment of cancer consists of daily irradiation of 2-Gy X-rays, 5 days a week for 5-8 weeks. To understand the characteristics of radioresistant cancer cells and to develop more effective radiotherapy, we established a series of novel, clinically relevant radioresistant (CRR) cells that continue to proliferate with 2-Gy X-ray exposure every 24 h for more than 30 days...

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PMID: 25098609
DOI: 10.1111/cas.12489

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