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Article

Proteomics of the radioresistant phenotype in head-and-neck cancer: Gp96 as a novel prediction marker and sensitizing target for radiotherapy.

International journal of radiation oncology, biology, physics - 1 Sept 2010

Lin Ting-Yang, Chang Joseph Tung-Chieh, Wang Hung-Ming, Chan Shih-Hsuan, Chiu Chi-Ching, Lin Chien-Yu, Fan Kang-Hsing, Liao Chun-Ta, Chen I-How, Liu Tsan Z, Li Hsiao-Fang, Cheng Ann-Joy

Abstract excerpt

PURPOSE: Radiotherapy is an integral part of the treatment modality for head-neck cancer (HNC), but in some cases the disease is radioresistant. We designed this study to identify molecules that may be involved in this resistance. METHODS AND MATERIALS: Two radioresistant sublines were established by fractionated irradiation of the HNC cell lines, to determine differentially proteins between parental and...

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PMID: 20615631
DOI: 10.1016/j.ijrobp.2010.03.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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