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Article

2'-5'-Oligoadenylate synthetase single-nucleotide polymorphisms and haplotypes are associated with variations in immune responses to rubella vaccine.

Human immunology - 1 Apr 2010

Haralambieva Iana H, Dhiman Neelam, Ovsyannikova Inna G, Vierkant Robert A, Pankratz V Shane, Jacobson Robert M, Poland Gregory A

Abstract excerpt

Interferon-induced antiviral genes are crucial players in innate antiviral defense and potential determinants of immune response heterogeneity. We selected 114 candidate single-nucleotide polymorphisms (SNPs) from 12 antiviral genes using an LD tagSNP selection approach and genotyped them in a cohort of 738 school children immunized with two doses of rubella vaccine. Associations between SNPs/haplotypes and...

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Identifiers

PMID: 20079393
DOI: 10.1016/j.humimm.2010.01.004
PMCID: PMC2842477

Genes

OAS1
OAS3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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