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Article

Transforming growth factor-beta polymorphisms and serum level in the development of osteosarcoma.

DNA and cell biology - 1 Nov 2014

Xu Shaogang, Yang Shufeng, Sun Guojing, Huang Wanxin, Zhang Yelong

Abstract excerpt

The transforming growth factor-beta (TGF-β) signaling pathway plays critical roles in the development of various diseases. The current study investigated whether TGF-β was involved in the pathogenesis of osteosarcoma from the genetic polymorphism perspective and serum level perspective. We first examined two TGF-β1 polymorphisms, rs1800469C/T and rs1800470T/C, in 202 osteosarcoma patients and 216 healthy...

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Identifiers

PMID: 25098449
DOI: 10.1089/dna.2014.2527

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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