Article
Effect of mite allergen immunotherapy on the altered phenotype of dendritic cells in allergic asthmatic children.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology - 1 Feb 2013
Wang Chuang-Ming, Chuang Jing-Jing
Abstract excerpt
BACKGROUND: Allergic asthma is a T(H)2 inflammatory disease. Dendritic cells (DCs) play key roles in the T(H)1/T(H)2 balance. Allergen specific immunotherapy (SIT) has the potential to modify the course of allergy because the ratio of T(H)1 to T(H)2 cytokines produced is increased after SIT. OBJECTIVE: To determine how SIT affects DCs in children and to define novel parameters of this treatment. METHODS: We...
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