Article
Molecular pathogenesis of post-transplant acute kidney injury: assessment of whole-genome mRNA and miRNA profiles.
PloS one - 1 Jan 2014
Wilflingseder Julia, Sunzenauer Judith, Toronyi Eva, Heinzel Andreas, Kainz Alexander, Mayer Bernd, Perco Paul, Telkes Gábor, Langer Robert M, Oberbauer Rainer
Abstract excerpt
Acute kidney injury (AKI) affects roughly 25% of all recipients of deceased donor organs. The prevention of post-transplant AKI is still an unmet clinical need. We prospectively collected zero-hour, indication as well as protocol kidney biopsies from 166 allografts between 2011 and 2013. In this cohort eight cases with AKI and ten matched allografts without pathology serving as control group were identified with...
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