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Cardiac regeneration using pluripotent stem cells—Progression to large animal models

6 Jul 2014

Abstract excerpt

Pluripotent stem cells (PSCs) have indisputable cardiomyogenic potential and therefore have been intensively investigated as a potential cardiac regenerative therapy. Current directed differentiation protocols are able to produce high yields of cardiomyocytes from PSCs and studies in small animal models of cardiovascular disease have proven sustained engraftment and functional efficacy. Therefore, the time is...

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PMID: 25087896
DOI: 10.1016/j.scr.2014.06.005

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