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Regeneration of Nonhuman Primate Hearts With Human Induced Pluripotent Stem Cell–Derived Cardiac Spheroids

26 Apr 2024

Abstract excerpt

BACKGROUND: The clinical application of human induced pluripotent stem cell–derived cardiomyocytes (CMs) for cardiac repair commenced with the epicardial delivery of engineered cardiac tissue; however, the feasibility of the direct delivery of human induced pluripotent stem cell–derived CMs into the cardiac muscle layer, which has reportedly induced electrical integration, is unclear because of concerns about...

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PMID: 38666382
DOI: 10.1161/circulationaha.123.064876

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