Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Oncogenic ras-driven cancer cell vesiculation leads to emission of double-stranded DNA capable of interacting with target cells.

Biochemical and biophysical research communications - 22 Aug 2014

Lee Tae Hoon, Chennakrishnaiah Shilpa, Audemard Eric, Montermini Laura, Meehan Brian, Rak Janusz

Abstract excerpt

Cell free DNA is often regarded as a source of genetic cancer biomarkers, but the related mechanisms of DNA release, composition and biological activity remain unclear. Here we show that rat epithelial cell transformation by the human H-ras oncogene leads to an increase in production of small, ex...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigens, Polyomavirus Transforming
Share to Cell Transformation, Neoplastic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromatin

Share to Exosomes

Share to Genes, ras

Share to Intestinal Mucosa

Share to Microscopy, Electron, Transmission

Share to Sphingomyelin Phosphodiesterase

Source

Identifiers

PMID: 25086355
DOI: 10.1016/j.bbrc.2014.07.109

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25086355-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Oncogenic ras-driven cancer cell vesiculation leads to emission of double-stranded DNA capable of interacting with target cells.PMID 25086355Read ↗

Unravelling the Significance of Extracellular Vesicle‐Associated DNA in Cancer Biology and Its Potential Clinical ApplicationsSemantic proximity Read ↗

Extracellular vesicles from genetically unstable, oncogene-driven cancer cells trigger micronuclei formation in endothelial cells.Semantic proximity Read ↗

Extracellular vesicles mediate the horizontal transfer of an active LINE‐1 retrotransposonSemantic proximity Read ↗

Colorectal cancer-derived extracellular vesicles induce transformation of fibroblasts into colon carcinoma cellsSemantic proximity Read ↗

Release of cell-free DNA into the bloodstream leads to high levels of non-tumor plasma DNA during tumor progression in rats.Semantic proximity Read ↗

Characterization of exosome release and extracellular vesicle-associated miRNAs for human bronchial epithelial cells irradiated with high charge and energy ionsSemantic proximity Read ↗

Defined genetic events associated with the spontaneous in vitro transformation of ElA/Ras-expressing human IMR90 fibroblasts.Semantic proximity Read ↗

Extracellular vesicles – vehicles that spread cancer genesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.