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Article

Virus-helminth coinfection reveals a microbiota-independent mechanism of immunomodulation

18 Jul 2014

Abstract excerpt

The mammalian intestine is colonized by beneficial commensal bacteria and is a site of infection by pathogens, including helminth parasites. Helminths induce potent immunomodulatory effects, but whether these effects are mediated by direct regulation of host immunity or indirectly through eliciting changes in the microbiota is unknown. We tested this in the context of virus-helminth coinfection. Helminth...

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PMID: 25082704
DOI: 10.1126/science.1256942

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