Article
The neuroblastoma and ganglion components of nodular ganglioneuroblastoma are genetically similar: evidence against separate clonal origins.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Feb 2015
Angelini Paola, Baruchel Sylvain, Marrano Paula, Irwin Meredith S, Thorner Paul S
Abstract excerpt
Nodular ganglioneuroblastoma is characterized by a macroscopic nodule of neuroblastoma within a ganglioneuromatous component. These two components have been considered to originate from separate clones, with the neuroblastoma clone accounting for the clinical behavior of nodular ganglioneuroblastoma. In order to investigate the clonal origin of the cellular components (neuroblasts, ganglion cells, and Schwann...
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