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Article

Large cell neuroblastoma: a distinct phenotype of neuroblastoma with aggressive clinical behavior.

Cancer - 15 Jan 2004

Tornóczky Tamás, Kálmán Endre, Kajtár Pál G, Nyári Tibor, Pearson Andrew D J, Tweddle Deborah A, Board Julian, Shimada Hiroyuki

Abstract excerpt

BACKGROUND: Among cases of undifferentiated and poorly differentiated tumors in the neuroblastoma (Schwannian stroma-poor) category, the authors histologically identified a group of rare tumors, known as large cell neuroblastomas (LCNs), that are composed of large cells with sharply outlined nuclear membranes and 1-4 prominent nucleoli. METHODS: Histologic and immunohistochemical features of LCN were...

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Source

Identifiers

PMID: 14716776
DOI: 10.1002/cncr.20005

Genes

MYCN

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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