Article
Prediction of HIV drug resistance from genotype with encoded three-dimensional protein structure.
BMC genomics - 1 Jan 2014
Yu Xiaxia, Weber Irene T, Harrison Robert W
Abstract excerpt
BACKGROUND: Drug resistance has become a severe challenge for treatment of HIV infections. Mutations accumulate in the HIV genome and make certain drugs ineffective. Prediction of resistance from genotype data is a valuable guide in choice of drugs for effective therapy. RESULTS: In order to improve the computational prediction of resistance from genotype data we have developed a unified encoding of the protein...
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