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Article

Interplay of genetic risk (CHRNA5) and environmental risk (partner smoking) on cigarette smoking reduction.

Drug and alcohol dependence - 1 Oct 2014

Chen Li-Shiun, Baker Timothy B, Piper Megan E, Smith Stevens S, Gu Charles, Grucza Richard A, Smith George Davey, Munafo Marcus, Bierut Laura J

Abstract excerpt

BACKGROUND: This study tests whether the genetic predictor (CHRNA5 nicotine receptor gene variants) and an environmental risk factor (partner smoking) interact in the prediction of smoking reduction. METHODS: Subjects were from a community-based, longitudinal study of women (n=1856) who smoked before pregnancy, and a randomized comparative effectiveness smoking cessation trial (n=1065). Smoking reduction was...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25073833
DOI: 10.1016/j.drugalcdep.2014.06.027
PMCID: PMC4161618

Genes

CHRNA5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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