Article
Familial colorectal cancer: a review.
World journal of gastroenterology - 28 Jul 2014
Armelao Franco, de Pretis Giovanni
Abstract excerpt
Familial colorectal cancer constitutes a heterogeneous group of patients in whom the underlying molecular mechanism is still unknown. Predisposition to a such neoplasms in this setting seems to be due to common low-penetrance genetic components, but the role of genetic testing in clinical practice has to be determined. Although screening guidelines in this moderate-risk population are empiric, data obtained in...
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