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Article

miRNAs Affect the Expression of Innate and Adaptive Immunity Proteins in Celiac Disease

29 Jul 2014

Abstract excerpt

OBJECTIVES: microRNAs (miRNAs) are short RNAs that regulate gene expression in various processes, including immune response. Altered immune response is a pivotal event in the pathogenesis of celiac disease (CD), and miRNAs could have a role in modulating both innate and adaptive response to gluten in celiac patients. METHODS: We compared miRNA profiles in duodenal biopsies of controls and CD patients by miRNA...

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PMID: 25070052
DOI: 10.1038/ajg.2014.203

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