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Celiac disease biomarkers identified by transcriptome analysis of small intestinal biopsies

10 Aug 2018

Abstract excerpt

Establishing a celiac disease (CD) diagnosis can be difficult, such as when CD-specific antibody levels are just above cutoff or when small intestinal biopsies show low-grade injuries. To investigate the biological pathways involved in CD and select potential biomarkers to aid in CD diagnosis, RNA sequencing of duodenal biopsies from subjects with either confirmed Active CD (n = 20) or without any signs of CD (n...

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PMID: 30097691
DOI: 10.1007/s00018-018-2898-5

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