Article
microRNA profiles in coeliac patients distinguish different clinical phenotypes and are modulated by gliadin peptides in primary duodenal fibroblasts.
Clinical science (London, England : 1979) - 1 Mar 2014
Vaira Valentina, Roncoroni Leda, Barisani Donatella, Gaudioso Gabriella, Bosari Silvano, Bulfamante Gaetano, Doneda Luisa, Conte Dario, Tomba Carolina, Bardella Maria Teresa, Ferrero Stefano, Locatelli Martina, Elli Luca
Abstract excerpt
CD (coeliac disease) is a frequent autoimmune disorder of the small bowel, which is characterized by an immunological reaction against gluten and transglutaminase in genetically predisposed subjects. However, the molecular determinants underpinning CD pathogenesis are yet to be fully elucidated and little data are available about the involvement of miRNAs (microRNAs) in CD. In the present study, the duodenal...
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