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Article

Genome-wide analysis of DNA methylation in subjects with type 1 diabetes identifies epigenetic modifications associated with proliferative diabetic retinopathy.

BMC medicine - 6 Aug 2015

Agardh Elisabet, Lundstig Annika, Perfilyev Alexander, Volkov Petr, Freiburghaus Tove, Lindholm Eero, Rönn Tina, Agardh Carl-David, Ling Charlotte

Abstract excerpt

BACKGROUND: Epigenetic variation has been linked to several human diseases. Proliferative diabetic retinopathy (PDR) is a major cause of vision loss in subjects with diabetes. However, studies examining the association between PDR and the genome-wide DNA methylation pattern are lacking. Our aim was to identify epigenetic modifications that associate with and predict PDR in subjects with type 1 diabetes (T1D)....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26248552
DOI: 10.1186/s12916-015-0421-5
PMCID: PMC4527111

Genes

AHRR
BCOR
GIPR
GLRA1
CHN2
GPX1
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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