Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Direct Genesis of Functional Rodent and Human Schwann Cells from Skin Mesenchymal Precursors

19 Jun 2014

Abstract excerpt

Recent reports of directed reprogramming have raised questions about the stability of cell lineages. Here, we have addressed this issue, focusing upon skin-derived precursors (SKPs), a dermally derived precursor cell. We show by lineage tracing that murine SKPs from dorsal skin originate from mesenchymal and not neural crest-derived cells. These mesenchymally derived SKPs can, without genetic manipulation,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Hair Growth and Disorders
Share to Nerve injury and regeneration
Share to Neurogenesis and neuroplasticity mechanisms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25068124
DOI: 10.1016/j.stemcr.2014.05.011

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Direct Genesis of Functional Rodent and Human Schwann Cells from Skin Mesenchymal PrecursorsPMID 25068124Read ↗

Isolation and characterization of multipotent skin-derived precursors from human skin.Semantic proximity Read ↗

Schwann cell precursors contribute to skeletal formation during embryonic development in mice and zebrafishSemantic proximity Read ↗

Neural crest–derived cells with stem cell features can be traced back to multiple lineages in the adult skinSemantic proximity Read ↗

Neural crest stem cells undergo multilineage differentiation in developing peripheral nerves to generate endoneurial fibroblasts in addition to Schwann cells.Semantic proximity Read ↗

Directly induced human Schwann cell precursors as a valuable source of Schwann cellsSemantic proximity Read ↗

Dermis‐derived stem cells: a source of epidermal melanocytes and melanoma?Semantic proximity Read ↗

A Highly Enriched Niche of Precursor Cells with Neuronal and Glial Potential Within the Hair Follicle Dermal Papilla of Adult SkinSemantic proximity Read ↗

Generation of Schwann cell derived melanocytes from hPSCs identifies pro-metastatic factors in melanomaSemantic proximity Read ↗

Skin-Derived Precursors Differentiate Into Skeletogenic Cell Types and Contribute to Bone RepairSemantic proximity Read ↗

Dermal fibroblast in cutaneous development and healingSemantic proximity Read ↗

Humanized neurofibroma model from induced pluripotent stem cells delineates tumor pathogenesis and developmental origins.Semantic proximity Read ↗

Single-Cell RNA Profiling of Human Skin Reveals Age-Related Loss of Dermal Sheath Cells and Their Contribution to a Juvenile PhenotypeSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.