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Schwann cell precursors contribute to skeletal formation during embryonic development in mice and zebrafish

8 Jul 2019

Abstract excerpt

Immature multipotent embryonic peripheral glial cells, the Schwann cell precursors (SCPs), differentiate into melanocytes, parasympathetic neurons, chromaffin cells, and dental mesenchymal populations. Here, genetic lineage tracing revealed that, during murine embryonic development, some SCPs detach from nerve fibers to become mesenchymal cells, which differentiate further into chondrocytes and mature osteocytes....

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PMID: 31285319
DOI: 10.1073/pnas.1900038116

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