Article
Detection and analysis of recombination in GII.4 norovirus strains causing gastroenteritis outbreaks in Alberta.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Oct 2014
Hasing Maria E, Hazes Bart, Lee Bonita E, Preiksaitis Jutta K, Pang Xiaoli L
Abstract excerpt
Recombination is an important mechanism generating genetic diversity in norovirus (NoV) that occurs commonly at the NoV polymerase-capsid (ORF1/2) junction. The genotyping method based on partial ORF2 sequences currently used to characterize circulating NoV strains in gastroenteritis outbreaks in Alberta cannot detect such recombination events and provides only limited information on NoV genetic evolution. The...
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