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Article

Divergent evolution of norovirus GII/4 by genome recombination from May 2006 to February 2009 in Japan.

Journal of virology - 1 Aug 2010

Motomura Kazushi, Yokoyama Masaru, Ode Hirotaka, Nakamura Hiromi, Mori Hiromi, Kanda Tadahito, Oka Tomoichiro, Katayama Kazuhiko, Noda Mamoru, Tanaka Tomoyuki, Takeda Naokazu, Sato Hironori

Abstract excerpt

Norovirus GII/4 is a leading cause of acute viral gastroenteritis in humans. We examined here how the GII/4 virus evolves to generate and sustain new epidemics in humans, using 199 near-full-length GII/4 genome sequences and 11 genome segment clones from human stool specimens collected at 19 sites in Japan between May 2006 and February 2009. Phylogenetic studies demonstrated outbreaks of 7 monophyletic GII/4...

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Identifiers

PMID: 20534859
DOI: 10.1128/JVI.02125-09
PMCID: PMC2916515

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