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Article

Recombination within the Pandemic Norovirus GII.4 Lineage

27 Mar 2013

Abstract excerpt

Norovirus (NoV) is the leading cause of viral gastroenteritis globally. Since 1996, NoV variants of a single genetic lineage, GII.4, have been associated with at least six pandemics of acute gastroenteritis and caused between 62 and 80% of all NoV outbreaks. The emergence of these novel GII.4 variants has been attributed to rapid evolution and antigenic variation in response to herd immunity; however, the...

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PMID: 23536665
DOI: 10.1128/jvi.03464-12

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