Article
Overexpression of autophagy-related 16-like 1 in patients with oral squamous cell carcinoma.
Pathology oncology research : POR - 1 Apr 2015
Tang Jen-Yang, Hsi Edward, Huang Ya-Chun, Hsu Nicholas Chung-Heng, Yang Wen-Chi, Chang Hsueh-Wei, Chai Chee-Yin, Chu Pei-Yi
Abstract excerpt
Dyregulation of autophagy has been reported in various human cancers including oral squamous cell carcinoma (OSCC). The objective of this study was to link expression of autophagy-related 16-like 1 (ATG16L1), a protein essential for autophagosome formation, to clinical outcome in a cohort of 90 OSCC patients. Expression level of ATG16L1 was assessed by immunohistochemistry and an immunoreactivity score (IRS),...
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