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Newly Identified Cancer-Associated Role of Human Neuronal Growth Regulator 1 (NEGR1)

1 Jan 2014

Abstract excerpt

Neuronal growth regulator 1 (NEGR1) has become a great interest based on the recent findings that its genetic alteration is implicated in human obesity and human dyslexia. By analyzing the gene expression profiles of tumor biopsies and normal tissues, we identified NEGR1 as a commonly down-regulated gene in many types of human cancer tissues. NEGR1 contains a C-terminal GPI anchor attachment site and is primarily...

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PMID: 25057311
DOI: 10.7150/jca.8052

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