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Article

Bacterial Sensing, Cell Signaling, and Modulation of the Immune Response During Sepsis

7 Jul 2012

Abstract excerpt

Since the definition of systemic inflammatory response syndrome/sepsis was originally proposed, a large amount of new information has been generated showing a much more complex scenario of inflammatory and counterinflammatory responses during sepsis. Moreover, some fundamental mechanisms of sensing and destroying invading microorganisms have been uncovered, which include the discovery of TLR4 as the...

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PMID: 22777111
DOI: 10.1097/shk.0b013e318262c4b0

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