Article
[Association of the ABCB1 gene with risk for uveal melanoma].
Arkhiv patologii - 1 Jan 2000
Saakian S V, Amirian A G, Tsygankov A Iu, Loginov V I, Burdennyĭ A M
Abstract excerpt
The study investigated the association of the ABCB1 C3435T polymorphism gene with the risk for uveal melanoma (UM). Genotyping was carried out using the polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) analysis. All the tumors under study were histologically verified. The patients with UM were found to have a high frequency of predisposing alleles and genotypes of this polymorphism in...
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