Article
SCN5A mutations and polymorphisms in patients with ventricular fibrillation during acute myocardial infarction.
Molecular medicine reports - 1 Oct 2014
Boehringer Tim, Bugert Peter, Borggrefe Martin, Elmas Elif
Abstract excerpt
Mutations in the SCN5A gene encoding the Nav1.5 channel α-subunit are known to be risk factors of arrhythmia, including Brugada Syndrome and Long QT syndrome subtype 3. The present study focused on the role of SCN5A variants in the development of ventricular fibrillation (VF) during acute myocardial infarction (AMI). Since VF during AMI is the major cause of sudden death in the Western world, SCN5A mutations...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.