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Article

Polymorphism H558R in the human cardiac sodium channel SCN5A gene is associated with atrial fibrillation.

The Journal of international medical research - 1 Jan 2011

Chen L, Zhang W, Fang C, Jiang S, Shu C, Cheng H, Li F, Li H

Abstract excerpt

Atrial fibrillation (AF) is one of the most common sustained cardiac arrhythmias and its prevalence is increasing worldwide in line with the growing elderly population. Many single nucleotide polymorphisms and mutations are associated with AF, including the common loss-of-function histidine-558-to-arginine (H558R) polymorphism of the human cardiac sodium channel, voltage-gated, type V, α subunit (encoded by the...

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Identifiers

PMID: 22117993
DOI: 10.1177/147323001103900535

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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