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Proteomic Analysis of the <i>Enterococcus faecalis</i> V583 Strain and Clinical Isolate V309 under Vancomycin Treatment

4 Feb 2010

Abstract excerpt

To understand the molecular mechanisms of bacteria resistance to glycopeptides, we obtained proteomic profiles of vancomycin-resistant Enterococcus faecalis V583 (reference strain) and V309 (clinical isolate) passaged with and without the drug. The specificity and reversibility of vancomycin resistance genes induced in V583 and V309 were further studied over time. By semiquantitative RT-PCR of vancomycin-treated...

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PMID: 20128627
DOI: 10.1021/pr901216e

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