Article
The hMLH1 -93G>A promoter polymorphism is associates with outcomes in oral squamous cell carcinoma patients.
Annals of surgical oncology - 1 Dec 2014
Lin Li-Han, Lin Ming-Wei, Mar Kwei, Lin Chun-Shu, Ji Dar-Der, Lee Wei-Ping, Lee Herng-Sheng, Cheng Ming-Fang, Hsia Kan-Tai
Abstract excerpt
BACKGROUND: The aim of this study was to investigate the impact of hMLH1 polymorphisms on treatment outcomes in patients with oral squamous cell carcinoma (OSCC). METHODS: Genotypings were performed by direct DNA sequencing in peripheral blood leukocytes from 185 male OSCC patients. Patients received primary surgery with or without adjuvant radiotherapy. Two hMLH1 tag single nucleotide polymorphisms...
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