Article
Restoration of MBL-deficiency: redefining the safety, efficacy and viability of MBL-substitution therapy.
Molecular immunology - 1 Oct 2014
Keizer M P, Wouters D, Schlapbach L J, Kuijpers T W
Abstract excerpt
MBL-deficiency is a commonly occurring deficiency of the innate immune system, affecting a substantial part of the population and has been extensively studied. MBL appears to function as a disease modifier. The role of MBL in different conditions is context-dependent. Many clinical studies show conflicting results, which can be partially explained by different definitions of MBL-deficiency, including phenotype-...
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