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Article

Case Report: Different faces of LRBA deficiency in five Moroccan families.

Frontiers in immunology - 1 Jan 2026

Hbibi Mohamed, Elamine Ahamada, Benhsaien Ibtihal, Idrissi Mounia Lakhdar, Tizki Samira, Bakkouri Jalila El, Hida Moustapha, Ailal Fatima, Bousfiha Ahmed Aziz

Abstract excerpt

LPS-responsive beige-like anchor protein (LRBA) deficiency is a primary immunodeficiency belonging to the spectrum of common variable immunodeficiency disorders, frequently associated with immune dysregulation, autoimmunity, and lymphoproliferation. Its clinical presentation is highly heterogeneous, ranging from isolated autoimmune cytopenias to severe multisystem involvement. Here, we report five cases of LRBA...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 42148132
DOI: 10.3389/fimmu.2026.1807421
PMCID: PMC13175778

Genes

LRBA

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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