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Article

Variability and resistance mutations in the hepatitis C virus NS3 protease in patients not treated with protease inhibitors.

Memorias do Instituto Oswaldo Cruz - 1 Feb 2013

Zeminian Luciana Bonome, Padovani Juliana Lara, Corvino Sílvia Maria, Silva Giovanni Faria, Pardini Maria Inês de Moura Campos, Grotto Rejane Maria Tommasini

Abstract excerpt

The goal of treatment of chronic hepatitis C is to achieve a sustained virological response, which is defined as exhibiting undetectable hepatitis C virus (HCV) RNA levels in serum following therapy for at least six months. However, the current treatment is only effective in 50% of patients infected with HCV genotype 1, the most prevalent genotype in Brazil. Inhibitors of the serine protease non-structural...

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Share to Antiviral Agents
Share to Drug Resistance, Viral

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Hepatitis C, Chronic

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Share to RNA, Viral

Share to Viral Nonstructural Proteins

Source

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Identifiers

PMID: 23440108
DOI: 10.1590/s0074-02762013000100002
PMCID: PMC3974320

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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