Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

<scp>IGF</scp>‐I regulates the age‐dependent signaling peptide humanin

18 Jul 2014

Abstract excerpt

Aging is influenced by endocrine pathways including the growth hormone/insulin-like growth factor-1 (GH/IGF) axis. Mitochondrial function has also been linked to the aging process, but the relevant mitochondrial signals mediating the effects of mitochondria are poorly understood. Humanin is a novel signaling peptide that acts as a potent regulator of cellular stress responses and protects from a variety of in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to FOXO transcription factor regulation
Share to GDF15 and Related Biomarkers
Share to Nutrition and Health in Aging

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25040290
DOI: 10.1111/acel.12243

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

<scp>IGF</scp>‐I regulates the age‐dependent signaling peptide humaninPMID 25040290Read ↗

Humanin and Age-Related Diseases: A New Link?Semantic proximity Read ↗

The mitochondrial derived peptide humanin is a regulator of lifespan and healthspanSemantic proximity Read ↗

The emerging role of the mitochondrial-derived peptide humanin in stress resistanceSemantic proximity Read ↗

Naturally occurring mitochondrial-derived peptides are age-dependent regulators of apoptosis, insulin sensitivity, and inflammatory markersSemantic proximity Read ↗

Mitochondrial-derived peptide humanin as therapeutic target in cancer and degenerative diseasesSemantic proximity Read ↗

GH and IGF1: roles in energy metabolism of long-living GH mutant mice.Semantic proximity Read ↗

Mitochondrial-derived peptides in energy metabolismSemantic proximity Read ↗

Mitochondrial-derived peptides in aging and age-related diseasesSemantic proximity Read ↗

High-intensity interval exercise increases humanin, a mitochondrial encoded peptide, in the plasma and muscle of menSemantic proximity Read ↗

MOTS-c, the Most Recent Mitochondrial Derived Peptide in Human Aging and Age-Related DiseasesSemantic proximity Read ↗

Impact of Growth Hormone-Related Mutations on Mammalian AgingSemantic proximity Read ↗

Mitochondrial-Derived Peptides Exacerbate Senescence.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.