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Complement dysregulation in osteoporosis: a novel mechanism of osteoimmunology

2025-09-08

Abstract excerpt

Osteoporosis is a multifactorial metabolic bone disease characterized by bone remodeling imbalance, chronic inflammation, hormonal dysregulation, and immune microenvironment disturbance. Recent studies in osteoimmunology have revealed that the complement system, beyond its traditional anti-infective function, plays a crucial role in bone metabolism. Activation products such as C3a and C5a generated through the cla...

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Literature Corpus work
3fe12d6d-5487-5d37-a230-949776691bcb
DOI
10.22541/au.175731681.15303023/v1
Open publication

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Complement dysregulation in osteoporosis: a novel mechanism of osteoimmunologyDOI 10.22541/au.175731681.15303023/v1
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