Article
Joint association of nicotinic acetylcholine receptor variants with abdominal obesity in American Indians: the Strong Heart Family Study.
PloS one - 1 Jan 2014
Zhu Yun, Yang Jingyun, Yeh Fawn, Cole Shelley A, Haack Karin, Lee Elisa T, Howard Barbara V, Zhao Jinying
Abstract excerpt
Cigarette smoke is a strong risk factor for obesity and cardiovascular disease. The effect of genetic variants involved in nicotine metabolism on obesity or body composition has not been well studied. Though many genetic variants have previously been associated with adiposity or body fat distribution, a single variant usually confers a minimal individual risk. The goal of this study is to evaluate the joint...
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