Article
[Study of codon 72 of p53 gene as a risk-factor in cervical cancer in Senegal].
Bulletin du cancer - 1 Sept 2014
Ndiaye Rokhaya, Dem Ahmadou, Mbaye Pape Matar, Guèye Papa Madièye, Diop Gora, Diop Papa Amadou, Faye Oumar
Abstract excerpt
Beside human papilloma virus infection, several genetic factors have been involved in susceptibility to cervical cancer. The arginine allele at codon 72 in p53 tumor suppressor gene has been reported to be a risk-factor in different ethnic groups. Our aim was to study this polymorphism as a risk-factor in Senegal. We conducted a case-control association study by recruiting 30 patients with cervical cancer...
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