Article
Dataset size and composition impact the reliability of performance benchmarks for peptide-MHC binding predictions.
BMC bioinformatics - 14 Jul 2014
Kim Yohan, Sidney John, Buus Søren, Sette Alessandro, Nielsen Morten, Peters Bjoern
Abstract excerpt
BACKGROUND: It is important to accurately determine the performance of peptide:MHC binding predictions, as this enables users to compare and choose between different prediction methods and provides estimates of the expected error rate. Two common approaches to determine prediction performance are cross-validation, in which all available data are iteratively split into training and testing data, and the use of...
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