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Article

A comprehensive analysis of the IEDB MHC class-I automated benchmark.

Briefings in bioinformatics - 18 Jul 2022

Trevizani Raphael, Yan Zhen, Greenbaum Jason A, Sette Alessandro, Nielsen Morten, Peters Bjoern

Abstract excerpt

In 2014, the Immune Epitope Database automated benchmark was created to compare the performance of the MHC class I binding predictors. However, this is not a straightforward process due to the different and non-standardized outputs of the methods. Additionally, some methods are more restrictive regarding the HLA alleles and epitope sizes for which they predict binding affinities, while others are more...

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PMID: 35794711
DOI: 10.1093/bib/bbac259
PMCID: PMC9618166

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