Article
Effect of Taiwan mutation (D7H) on structures of amyloid-β peptides: replica exchange molecular dynamics study.
The journal of physical chemistry. B - 31 Jul 2014
Truong Phan Minh, Viet Man Hoang, Nguyen Phuong H, Hu Chin-Kun, Li Mai Suan
Abstract excerpt
Recent experiments have shown that the Taiwan mutation (D7H) slows the fibril formation of amyloid peptides Aβ40 and Aβ42. Motivated by this finding, we have studied the influence of D7H mutation on structures of Aβ peptide monomers using the replica exchange molecular dynamics simulations with O...
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