Article
Complement C3 polymorphism is associated with the susceptibility of myasthenia gravis in Chinese adult patients.
Journal of neuroimmunology - 15 Apr 2021
Yue Yao-Xian, Gao Xiang, Tang Tian-Ping, Xie Yanchen, Gu Chuan-Kai, Hao Hong-Jun, Li Hong-Yan, Ding Xiao-Jun, Song Min, Guo Shou-Gang, Li Hai-Feng
Abstract excerpt
Complement component 3 (C3) had been proved to be involved in the pathogenesis and exacerbation of both myasthenia gravis (MG) patients and experimental autoimmune myasthenia gravis (EAMG) models. We evaluated the underlying association between five SNPs (rs344555, rs7951, rs3745568, rs366510 and rs163913) in C3 gene and Chinese adult MG patients. Our study consisted of 409 adult MG patients and 487 healthy...