Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A mitochondrial CO2-adenylyl cyclase-cAMP signalosome controls yeast normoxic cytochrome c oxidase activity.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Oct 2014

Hess Kenneth C, Liu Jingjing, Manfredi Giovanni, Mühlschlegel Fritz A, Buck Jochen, Levin Lonny R, Barrientos Antoni

Abstract excerpt

Mitochondria, the major source of cellular energy in the form of ATP, respond to changes in substrate availability and bioenergetic demands by employing rapid, short-term, metabolic adaptation mechanisms, such as phosphorylation-dependent protein regulation. In mammalian cells, an intramitochondrial CO2-adenylyl cyclase (AC)-cyclic AMP (cAMP)-protein kinase A (PKA) pathway regulates aerobic energy production. One...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenosine Diphosphate
Share to Allosteric Regulation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Carbon Dioxide

Share to Cell Hypoxia

Share to Cyclic AMP

Share to Cyclic AMP-Dependent Protein Kinases

Share to Electron Transport Complex IV

Share to Mitochondrial Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 25002117
DOI: 10.1096/fj.14-252890
PMCID: PMC4202101

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A mitochondrial CO2-adenylyl cyclase-cAMP signalosome controls yeast normoxic cytochrome c oxidase activity.PMID 25002117Read ↗

Respiratory chain complex I, a main regulatory target of the cAMP/PKA pathway is defective in different human diseases.Semantic proximity Read ↗

Modulation of mitochondrial protein phosphorylation by soluble adenylyl cyclase ameliorates cytochrome oxidase defects.Semantic proximity Read ↗

TORC1 integrates metabolic state transitions during agingSemantic proximity Read ↗

Aconitase couples metabolic regulation to mitochondrial DNA maintenance.Semantic proximity Read ↗

Functional and Regulatory Profiling of Energy Metabolism in Fission YeastSemantic proximity Read ↗

Influence of inositol pyrophosphates on cellular energy dynamics.Semantic proximity Read ↗

Integration of the tricarboxylic acid (TCA) cycle with cAMP signaling and Sfl2 pathways in the regulation of CO2 sensing and hyphal development in Candida albicansSemantic proximity Read ↗

Synthesis of cytochrome c oxidase subunit 1 is translationally downregulated in the absence of functional F1F0-ATP synthase.Semantic proximity Read ↗

Increasing mitochondrial substrate-level phosphorylation can rescue respiratory growth of an ATP synthase-deficient yeast.Semantic proximity Read ↗

pH and the cAMP-dependent protein kinase mediate growth phase induction of the cytochrome c oxidase subunit VI gene, COX6, in Saccharomyces cerevisiae.Semantic proximity Read ↗

Functional and regulatory profiling of energy metabolism in fission yeast.Semantic proximity Read ↗

An NADH-controlled gatekeeper of ATP synthaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.