Article
Angiotensin II, type 2 receptor in the development of vesico-ureteric reflux.
BJU international - 1 Feb 1999
Hohenfellner K, Hunley T E, Yerkes E, Habermehl P, Hohenfellner R, Kon V
Abstract excerpt
OBJECTIVE: To investigate if mutation of the angiotensin II (Ang II) receptors AT2 is involved in primary vesico-ureteric reflux (VUR) in humans. PATIENTS AND METHODS: Genetic polymorphisms in the AT1 and AT2 receptors was evaluated in 23 patients having the most common congenital urological abnormality, namely primary congenital VUR. The occurrence of the A1166C transition in the AT1 receptor gene and the...
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