Article
High frequency of BRAF V600E mutations in ameloblastoma.
The Journal of pathology - 1 Apr 2014
Kurppa Kari J, Catón Javier, Morgan Peter R, Ristimäki Ari, Ruhin Blandine, Kellokoski Jari, Elenius Klaus, Heikinheimo Kristiina
Abstract excerpt
Ameloblastoma is a benign but locally infiltrative odontogenic neoplasm. Although ameloblastomas rarely metastasise, recurrences together with radical surgery often result in facial deformity and significant morbidity. Development of non-invasive therapies has been precluded by a lack of understanding of the molecular background of ameloblastoma pathogenesis. When addressing the role of ERBB receptors as...
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