Article
Genetics of osteoarthritis.
Reumatologia clinica - 1 Jan 2000
Rodriguez-Fontenla Cristina, Gonzalez Antonio
Abstract excerpt
Osteoarthritis (OA) is a complex disease caused by the interaction of multiple genetic and environmental factors. This review focuses on the studies that have contributed to the discovery of genetic susceptibility factors in OA. The most relevant associations discovered until now are discussed in detail: GDF-5, 7q22 locus, MCF2L, DOT1L, NCOA3 and also some important findings from the arcOGEN study. Moreover, the...
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