Article
REDOR constraints on the peptidoglycan lattice architecture of Staphylococcus aureus and its FemA mutant.
Biochimica et biophysica acta - 1 Jan 2015
Singh Manmilan, Kim Sung Joon, Sharif Shasad, Preobrazhenskaya Maria, Schaefer Jacob
Abstract excerpt
The peptidoglycan of Gram-positive bacteria consists of glycan chains with attached short peptide stems cross-linked to one another by glycyl bridges. The bridge of Staphylococcus aureus has five glycyl units and that of its FemA mutant has one. These long- and short-bridge cross-links create totally different cell-wall architectures. S. aureus and its FemA mutant grown in the presence of an alanine-racemase...
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