Article
Gene structure and promoter variation of expressed and nonexpressed variants of the KIR2DL5 gene.
Journal of immunology (Baltimore, Md. : 1950) - 1 Dec 2000
Vilches C, Gardiner C M, Parham P
Abstract excerpt
Two variants of the novel KIR2DL5 gene (KIR2DL5.1 and.2) were identified in genomic DNA of a single donor. However, only the KIR2DL5.1 variant was transcribed in PBMC. In this study, analysis of seven additional donors reveals two new variants of the KIR2DL5 gene and indicates that transcription, or its lack, are consistently associated with particular variants of this gene. Comparison of the complete nucleotide...
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